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Wot no coronavirus thread? Part 2

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  • #1171
    Not nice, tho not the final word:

    Early evidence suggests the variant of coronavirus that emerged in the UK may be more deadly, Prime Minister Boris Johnson said.

    The data has been assessed by scientists on the New and Emerging Respiratory Virus Threats Advisory Group, which has briefed government.

    However, all the evidence remains at a preliminary stage.

    Studies have already shown it can spread more easily than other version of the virus.
    (...)
    from: https://www.bbc.com/news/health-55768627

    Blah

    Comment

    • -Jrabbit
      #1171.1
      -Jrabbit commented
      January 22, 2021, 13:54
      Editing a comment
      New and Emerging Respiratory Virus Threats Advisory Group -- NERVTAG!

      Now that's an acronym!
    • Uncle Sparky
      #1171.2
      Uncle Sparky commented
      January 22, 2021, 16:07
      Editing a comment
      Oh great... now everyone will want the new deadlier variant without the proper infrastructure .

      Whose building Thunderdome?
  • #1172
    Good news everybody. A small manufacturing company in PEI Canada has just laid off 30 staff. Why is that good news? They make throat lozenges.
    Sales have tanked. Canadians are practicing good hygiene, avoiding crowds, wearing facemasks in groups, and, if they are sick, are staying home.
    Flu hospitalizations are way down, and cold patent medicine sales are way down.
    There's nothing wrong with the dream, my friend, the problem lies with the dreamer.

    Comment

    • #1173
      US cases continue adding over 1million per week. US deaths are now at 441,808 and growing at over 3,416 deaths per day (7-day moving average).

      Equivalent city wiped out by COVID: Oakland (433K) or Minneapolis (429K).
      Apolyton's Grim Reaper 2008, 2010 & 2011
      RIP lest we forget... SG (2) and LaFayette -- Civ2 Succession Games Brothers-in-Arms

      Comment

      • #1174
        The good thing is, that finally the new CoViD-19 cases per day go down (in the USA as well as in germany)

        In the USA the 7 days avg dropped from a peak in Jan 11 of 250k to now just 170k (although it currently just results in the active corona cases hitting a plateau at 9.8 mio)

        United States COVID - Coronavirus Statistics - Worldometer
        https://www.worldometers.info/coronavirus/country/us/
        United States Coronavirus update with statistics and graphs: total and new cases, deaths per day, mortality and recovery rates, current active cases, recoveries, trends and timeline.


        In germany (where we have a lockdown since the beginning of the year) the 7 days avg since its peak on Dec 17 (with 25k) has now dropped to just 12k and we also finally see a drop in active cases from 254k on Dec 17 to currently just 265k

        Germany COVID - Coronavirus Statistics - Worldometer
        https://www.worldometers.info/coronavirus/country/germany/
        Germany Coronavirus update with statistics and graphs: total and new cases, deaths per day, mortality and recovery rates, current active cases, recoveries, trends and timeline.





        Tamsin (Lost Girl): "I am the Harbinger of Death. I arrive on winds of blessed air. Air that you no longer deserve."
        Tamsin (Lost Girl): "He has fallen in battle and I must take him to the Einherjar in Valhalla"

        Comment

        • #1175
          It's interesting that these second peaks don't have as high death rate as the first ones.
          Indifference is Bliss

          Comment

          • dannubis
            #1175.1
            dannubis commented
            January 30, 2021, 05:08
            Editing a comment
            Yeah, but they plateau at a much higher level so over the peak they are more deadly (at least in Belgium)
          • -Jrabbit
            #1175.2
            -Jrabbit commented
            January 30, 2021, 15:13
            Editing a comment
            Over the course of 10-11 months, the medical community has gotten a lot better at dealing with this disease. In addition, increased testing mean that more infections are caught in early stages when easier to treat.
        • #1176
          Peerhaps because the hospitaals are better prepared (more ICUs with respirators) ... or because the age structure of infected people now is different (less old people and more middle aged/young people who get infected (and have a better chance for a non serious progression of the disease)) ... or perhaps both of these effects combined

          (at least tjhat what I would assume)
          Tamsin (Lost Girl): "I am the Harbinger of Death. I arrive on winds of blessed air. Air that you no longer deserve."
          Tamsin (Lost Girl): "He has fallen in battle and I must take him to the Einherjar in Valhalla"

          Comment

          • #1177
            Originally posted by Proteus_MST View Post
            Peerhaps because the hospitaals are better prepared (more ICUs with respirators) ... or because the age structure of infected people now is different (less old people and more middle aged/young people who get infected (and have a better chance for a non serious progression of the disease)) ... or perhaps both of these effects combined

            (at least tjhat what I would assume)
            My hypothesis is that the more susceptible people have died, so there's fewer of them, and also that there's much more testing (especially on unsymptomatic people) and so the total population is higher.
            Indifference is Bliss

            Comment

            • #1178
              Originally posted by N35t0r View Post
              It's interesting that these second peaks don't have as high death rate as the first ones.
              Isn't it obvious? We were not ventilating right earlier and we didn't know good tools. Now we have steroids and plasma and more...

              JM
              Jon Miller-
              I AM.CANADIAN
              GENERATION 35: The first time you see this, copy it into your sig on any forum and add 1 to the generation. Social experiment.

              Comment

              • #1179
                Interesting study here.

                Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A


                Abstract

                SARS-CoV-2 viral proteins interact with the eukaryotic translation machinery and inhibitors of translation have potent antiviral effects. Here we report that the drug plitidepsin (aplidin), which has limited clinical approval, possesses antiviral activity (IC90 = 0.88 nM) 27.5-fold more potent than remdesivir against SARS-CoV-2 in vitro, with limited toxicity in cell culture. Through the use of a drug resistant mutant, we show that the antiviral activity of plitidepsin against SARS-CoV-2 is mediated through inhibition of the known target eEF1A. We demonstrate the in vivo efficacy of plitidepsin treatment in two mouse models of SARS-CoV-2 infection with a reduction of viral replication in the lungs by two orders of magnitude using prophylactic treatment. Our results indicate that plitidepsin is a promising therapeutic candidate for COVID-19.
                Much more to read at the site.
                With or without religion, you would have good people doing good things and evil people doing evil things. But for good people to do evil things, that takes religion.

                Steven Weinberg

                Comment

                • #1180
                  56 Canadians have been diagnosed with the seasonal flu so far this winter, compared to over 2,600 last winter as a side effect of behavioral changes under COVID.
                  There's nothing wrong with the dream, my friend, the problem lies with the dreamer.

                  Comment

                • #1181
                  University College, London. Tracking flu numbers in England. It's about 20-30% of the usual volume for this time of year.

                  Flu Detector (i-sense flu)
                  https://fludetector.cs.ucl.ac.uk/

                  https://fludetector.cs.ucl.ac.uk/?so...ay&smoothing=0
                  One day Canada will rule the world, and then we'll all be sorry.

                  Comment

                  • #1182
                    Captain Tom Moore has died of Covid.

                    After raising £33m for the NHS (because the govt didn’t raise funding) to fight Covid. Tragic irony.
                    One day Canada will rule the world, and then we'll all be sorry.

                    Comment

                    • #1183
                      Got my 1st covid quickie(=test) today

                      But it turned out to be a negative thing
                      Blah
                      • Likes 1

                      Comment

                      • Thoth
                        #1183.1
                        Thoth commented
                        February 4, 2021, 15:09
                        Editing a comment
                        Glad to hear it. Covid is no fun at all.
                      • -Jrabbit
                        #1183.2
                        -Jrabbit commented
                        February 4, 2021, 17:56
                        Editing a comment
                        I've been getting tested monthly since around August or September. Better safe than sorry.
                        Next step: vaccine. Registered and waiting...
                    • #1184
                      Amazing news from Israel: a cure for the common COVID had 96% efficacy on 30 infected volunteers in its Phase I testing.

                      Pretty damned cool, and maybe a light at the end of this dark, dark tunnel. Phase II testing (full double-blind technique) is next.

                      The drug is EXO-CD24, and it's administered direct to the lungs with an inhaler. Space laser optional.
                      Apolyton's Grim Reaper 2008, 2010 & 2011
                      RIP lest we forget... SG (2) and LaFayette -- Civ2 Succession Games Brothers-in-Arms

                      Comment

                      • #1185
                        this confinement is getting on my nervres big time

                        Comment

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