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  • #1

    Get On The Grid

    World Community Grid is a new computing grid being launched by IBM and United Devices, to harness the idle processor cycles of people's computers to do research that benefits humanity.

    The current project is called the "Human Proteome Folding" project:
    The Human Proteome Folding project will provide scientists with data that predicts the shape of a very large number of human proteins. These predictions will give scientists the clues they need to identify the biological functions of individual proteins within the human body. With an understanding of how each protein affects human health, scientists can develop new cures for human diseases such as cancer, HIV/AIDS, SARS, and malaria.

    More information is available here: http://www.worldcommunitygrid.org/pr...e_project.html

    This does not affect your computer's performance, because it only uses processor cycles that are otherwise wasted on doing nothing.


    Step 1: Join (download, install, register): http://www.worldcommunitygrid.org/jo.../join_now.html
    Step 2: Join the Apolyton team: http://www.worldcommunitygrid.org/te...Id=635XNJBR9N1

    Human Proteome Folding is 70% done:


    When this project completes in around December, a few new projects will be launched. Various research organizations from around the world have submitted proposals, and they are being evaluated as we speak, with announcements of the supported proposals expected in late September.

    So use your spare cycles, join today.
    "The issue is there are still many people out there that use religion as a crutch for bigotry and hate. Like Ben."
    Ben Kenobi: "That means I'm doing something right. "
    Tags: None
  • #2
    6-27-2005
    Seattle

    Update from the Institute for SystemsBiology

    Work completed:

    We have completed 60-72% of the work we plan to process in this phase of the human proteome folding project. That means we’ve processed a huge amount of work that when combined and post-processed here at the ISB results in 3D-structure predictions for over 53,000 protein domains taken from proteins in all complete genome sequences. Again, these domains are the least annotated sequences out there, so this info should be a major source of insight for figuring out what these proteins do. We have two grids devoted to this project (one operated by IBM, the worldcommunitygrid.org, and one operated by United Devices, grid.org). So far IBM has returned 49 batches of work resulting in 49,000 structure predictions, while UD has returned 14 batches. We are projected to finish the work in december at this rate (the grid has grown a bit slower than we thought it would, so tell you’re friends).

    Biology interface:

    We have begun the final stage of development for this project, the front end that will display results to biologists. Two programers at the ISB have now begun the process of integrating the results we get from the grid with the myriad other types of biological data using the data visualization and integration platform Cytoscape (cytoscape.org). The functional implications of any given structure prediction are best interpreted in light of everything else we know about a given protein. This front end will allow biologists to efficiently evaluate not just the structure and sequence matches for a given protein, but also its context in the cellular network. Work will begin on a subset of 5 organisms including yeast, human and malaria, but will eventually include all organisms on the grid ... more on this soon.


    Richard Bonneau
    Sr. Scientist
    ISB, Seattle
    "The issue is there are still many people out there that use religion as a crutch for bigotry and hate. Like Ben."
    Ben Kenobi: "That means I'm doing something right. "

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    • #3
      That's amazingly interesting work. Makes you wonder just how far are we from having a single computer compute this for a very short time. The biotechnological meanings will be insane.
      urgh.NSFW

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      • #4
        Know anything that's devilishly good at finding micro-RNA fragments? Cause that would make my job a hell of a lot easier.
        Exult in your existence, because that very process has blundered unwittingly on its own negation. Only a small, local negation, to be sure: only one species, and only a minority of that species; but there lies hope. [...] Stand tall, Bipedal Ape. The shark may outswim you, the cheetah outrun you, the swift outfly you, the capuchin outclimb you, the elephant outpower you, the redwood outlast you. But you have the biggest gifts of all: the gift of understanding the ruthlessly cruel process that gave us all existence [and the] gift of revulsion against its implications.
        -Richard Dawkins

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        • #5
          I don't care about benefitting humanity. I care about playing computer games more.

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          • #6
            I did this for a while ... but there's one downside to it, for people with Athlon 2200+ Tbirds in non-water cooled systems, and 80-90 degree (F) (31+ degree C) rooms ...

            It caused my computer to blue-screen-of-death crash fairly regularly (every three-four hours of runtime, faster after first crash of course)
            <Reverend> IRC is just multiplayer notepad.
            I like your SNOOPY POSTER! - While you Wait quote.

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            • #7
              But then...

              [q=Asher]This does not affect your computer's performance, because it only uses processor cycles that are otherwise wasted on doing nothing.[/q]

              So you can do both at the same time.
              Civilization II: maps, guides, links, scenarios, patches and utilities (+ Civ2Tech and CivEngineer)

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              • #8
                Originally posted by snoopy369
                I did this for a while ... but there's one downside to it, for people with Athlon 2200+ Tbirds in non-water cooled systems, and 80-90 degree (F) (31+ degree C) rooms ...

                It caused my computer to blue-screen-of-death crash fairly regularly (every three-four hours of runtime, faster after first crash of course)
                Sounds like your Athlon is running too hot under load.
                "The issue is there are still many people out there that use religion as a crutch for bigotry and hate. Like Ben."
                Ben Kenobi: "That means I'm doing something right. "

                Comment

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