If you're really gonna start in 150 AD and end in 1453 AD, please do something about the Persians. The time the Persians themselves were true enemies to the Romans was 'only' between 224 and ca. 630. Before, you should have the Parthians in, and before you ask, it would be inaccurate to jam them into one civ; though that might still work, but after 630, you should exclude them entirely! Their place would be taken by, chronologically, Arabs (630-ca.1000), Turks (1000-1220), and Mongols (1220-1500).
And apart from that, choosing Chosroes II as their leader isn't the best idea either. He wasn't such a great king as it is always proclaimed. He was really the one entirely responsible for the downfall of the Sasanian empire. Shapur I or II would be the, IMHO, best choices, as these two kings were really the ones who gave the Romans a hard time (S. II would be the very best choice, as he actually subdued the East Romans to tributary dependance, which lasted until Chosroes I).
And apart from that, choosing Chosroes II as their leader isn't the best idea either. He wasn't such a great king as it is always proclaimed. He was really the one entirely responsible for the downfall of the Sasanian empire. Shapur I or II would be the, IMHO, best choices, as these two kings were really the ones who gave the Romans a hard time (S. II would be the very best choice, as he actually subdued the East Romans to tributary dependance, which lasted until Chosroes I).
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