P3 1GHz, haven't played lots (also, only really played enough 8 civs large maps to comment), but it's almost speed problem-less -- a varying delay while the AI moves (a problem everyone is having), and a two second or so delay when loading the advisor screen is my only complaint. I've got a nice graphics card (32 MB).
-- adaMada
EDIT: Added graphics card info.
-- adaMada
EDIT: Added graphics card info.
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