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apolyton biochemists and biologists: what is a holliday junction?
Wikipedia doesn't know, and no explanation is provided in the article I'm reading 
context: dna double crossover molecules
context: dna double crossover molecules
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Google knows all
"The nature of structural changes in DNA neccessary to result in
homologous genetic recombination were layed out by Holliday in 1964,
and in subsequent years the crossover-structures were visualized by
electron microscopy. The actual conformation of a DNA crossover was
speculated to be a four-way-junction with separate DNA helices, or
with stacked helices in either a parallel or an antiparallel
orientation of the helices. The models had to allow for branch
migration, else no exchange of genetic material would happen.
Homologous genetic recombination is a highly dynamic process, in
contrast to X-ray crystallography relaying on static structures. So it
took to the end of the previous millenium to get an atomic detail view
of relevant structures..."
http://www.biologie.uni-hamburg.de/l...day/4wjdna.htmExult in your existence, because that very process has blundered unwittingly on its own negation. Only a small, local negation, to be sure: only one species, and only a minority of that species; but there lies hope. [...] Stand tall, Bipedal Ape. The shark may outswim you, the cheetah outrun you, the swift outfly you, the capuchin outclimb you, the elephant outpower you, the redwood outlast you. But you have the biggest gifts of all: the gift of understanding the ruthlessly cruel process that gave us all existence [and the] gift of revulsion against its implications.
-Richard Dawkins -
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ah thx
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Beautiful thing the holliday junction.Exult in your existence, because that very process has blundered unwittingly on its own negation. Only a small, local negation, to be sure: only one species, and only a minority of that species; but there lies hope. [...] Stand tall, Bipedal Ape. The shark may outswim you, the cheetah outrun you, the swift outfly you, the capuchin outclimb you, the elephant outpower you, the redwood outlast you. But you have the biggest gifts of all: the gift of understanding the ruthlessly cruel process that gave us all existence [and the] gift of revulsion against its implications.
-Richard DawkinsComment
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During meosis, with two chromosomes becoming paired, DNA strands from the two chromosomes become interwinded at a cross-over point. Molecularly, the Holliday junction is where the combining happens - the place where the DNA strands cross each other.Solver, WePlayCiv Co-Administrator
Contact: solver-at-weplayciv-dot-com
I can kill you whenever I please... but not today. - The Cigarette Smoking ManComment
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oh ****
I'm reading "the flexibility of dna double crossover molecules", and I don't understand their procedure AT ALL - I mean, I understand "we added such-and-such", I just have no clue what it's all doing and why it works
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He goes to a HS for smart people. My God, I won't be learning about that stuff for at least another year.Originally posted by Japher
don't read such confussing stuff kuci... who do you think you are?
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nm, I figured out some of it and the rest is irreleventOriginally posted by Kuciwalker
oh ****
I'm reading "the flexibility of dna double crossover molecules", and I don't understand their procedure AT ALL - I mean, I understand "we added such-and-such", I just have no clue what it's all doing and why it works
w00t teh presentation was finished and is w00tlyComment
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You're one of those sissy zoology peopleOriginally posted by Odin
He goes to a HS for smart people. My God, I won't be learning about that stuff for at least another year.
Why would you ever study this stuff?
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Studying the origin of animal phyla is sissy to you?Originally posted by Kuciwalker
You're one of those sissy zoology people
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Zoology
Microbiology
That is all.Concrete, Abstract, or Squoingy?
"I don't believe in giving scripting languages because the only additional power they give users is the power to create bugs." - Mike Breitkreutz, FiraxisComment
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Someone send the boy some porn!!!Only feebs vote.Comment
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oh and me too please
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