okay so I don't play ToT but I would imagine some things same for all MP
Personally, I would run a timer, even if it's set like on 5 mins. because sometimes it will hang up on someone and if time is unlimited it's harder to get it going again, whereas otherwise it will usually kick over to the next turn when the time runs out.
the 2x2x vs 1x1x debate can rage forever as all have their proponents. Purists say 2x ruins the game (who needs to build granaries if yr food production already running amok?) Personally, I find it makes for a much faster game, which is usually the preference when running MP cause it's so hard to get anyone to finish a game anyhow.
My 2 pence on that